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Symbol
Name
ID
Espl1
extra spindle pole bodies 1, separase
MGI:2146156
Phenotype annotations related to cellular
Darker colors indicate more annotations

Mouse Phenotypes
abnormal male germ cell morphology
abnormal spermatid morphology
abnormal spermatocyte morphology
abnormal spermatogonia morphology
absent primordial germ cells
abnormal centrosome morphology
abnormal cell nucleus morphology
abnormal chromosome morphology
aneuploidy
abnormal mitosis
increased mitotic index
abnormal inner cell mass proliferation
decreased primordial germ cell proliferation
decreased cell proliferation
chromosomal instability
Availability Mouse Genotype
Espl1tm1.2Tno/Espl1tm1.2Tno
Tg(MMTV-Espl1)1Pati/0
Espl1tm1.1Tno/Espl1+  (conditional)
Espl1tm1.1Tno/Espl1tm1.2Tno  (conditional)
Espl1tm2Pzg/Espl1+
Meox2tm1(cre)Sor/Meox2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory