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Symbol
Name
ID
Mbd5
methyl-CpG binding domain protein 5
MGI:2138934
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Drooling
Feeding difficulties
Inappropriate laughter
Reduced social reciprocity
Autistic behavior
Polyphagia
Aggressive behavior
Bruxism
Recurrent hand flapping
Self-injurious behavior
Disease(s) Associated with MBD5
autosomal dominant intellectual developmental disorder 1

Mouse Phenotypes
behavior/neurological phenotype
abnormal learning/memory/conditioning
decreased exploration in new environment
abnormal response to novel object
increased grooming behavior
abnormal motor capabilities/coordination/movement
impaired coordination
decreased grip strength
decreased locomotor activity
abnormal social investigation
Availability Mouse Genotype
Mbd5Gt(Ayu21-B205)Imeg/Mbd5+ *
Mbd5tm1b(EUCOMM)Wtsi/Mbd5+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory