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Symbol
Name
ID

Sirt1
sirtuin 1
MGI:2135607

Phenotype annotations related to vision/eye

Darker colors indicate more annotations

Human Phenotypes	Abnormality of eye movement
Disease(s) Associated with SIRT1	Abnormality of eye movement
Huntington's disease

Mouse Phenotypes

abnormal lacrimal gland morphology

abnormal retina photoreceptor morphology

abnormal eye morphology

abnormal iris morphology

abnormal eye development

ocular hypotelorism

microphthalmia

abnormal eyelid morphology

narrow eye opening

eyelids fail to open

abnormal retina layer morphology

disorganized retina inner nuclear layer

disorganized retina outer nuclear layer

Availability

Mouse Genotype

Sirt1^{tm1b(EUCOMM)Wtsi}/Sirt1^{tm1b(EUCOMM)Wtsi}

Sirt1^tm1Fwa/Sirt1^tm1Fwa

Sirt1^tm1Mcby/Sirt1^tm1Mcby

Sirt1^tm2.1Fwa/Sirt1^tm2.1Fwa

Sirt1^tm2Fwa/Sirt1^tm2Fwa

Sirt1^tm3.1Mcby/Sirt1^tm3.1Mcby

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23