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Symbol
Name
ID
Sirt1
sirtuin 1
MGI:2135607
Phenotype annotations related to growth/size/body
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
abnormal palatal rugae morphology
short snout
decreased embryo size
growth/size/body region phenotype
decreased body weight
slow postnatal weight gain
increased body weight
abnormal head morphology
decreased body length
decreased susceptibility to age related obesity
decreased body size
postnatal growth retardation
Availability Mouse Genotype
Sirt1tm1.1Cxd/Sirt1tm1.1Cxd
Sirt1tm1.1Ygu/Sirt1tm1.1Ygu
Sirt1tm1Fwa/Sirt1tm1Fwa
Sirt1tm1Mcby/Sirt1tm1Mcby
Sirt1tm2.1Fwa/Sirt1tm2.1Fwa
Sirt1tm2.1Mcby/Sirt1tm2.1Mcby
Sirt1tm3.1Mcby/Sirt1tm3.1Mcby
Sirt1tm3Fwa/Sirt1tm3Fwa
Tg(Nes-cre)1Kln/0  (conditional)
Gt(ROSA)26Sortm1(Sirt1)Ktm/Gt(ROSA)26Sor+
Tg(Pomc1-cre)16Lowl/0  (conditional)
*
Gt(ROSA)26Sortm1(Sirt1)Ktm/Gt(ROSA)26Sor+
Tg(Agrp-cre)1Gsb/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory