Symbol
Name
ID

Arl3
ADP-ribosylation factor-like 3
MGI:1929699

Phenotype annotations related to vision/eye

Darker colors indicate more annotations

Human Phenotypes

Cystoid macular edema

Attenuation of retinal blood vessels

Posterior subcapsular cataract

Iris coloboma

Bone spicule pigmentation of the retina

Rod-cone dystrophy

Asteroid hyalosis

Vitreous floaters

Strabismus

Nystagmus

Oculomotor apraxia

Nyctalopia

Reduced visual acuity

Constriction of peripheral visual field

Ptosis

Disease(s) Associated with ARL3

Joubert syndrome

retinitis pigmentosa 83

Mouse Phenotypes

abnormal photoreceptor connecting cilium morphology

abnormal photoreceptor inner segment morphology

abnormal photoreceptor outer segment morphology

absent photoreceptor outer segment

short photoreceptor outer segment

abnormal retina rod cell outer segment morphology

retina cone cell degeneration

abnormal retina rod cell morphology

retina rod cell degeneration

abnormal retina morphology

thin retina inner nuclear layer

abnormal retina outer nuclear layer morphology

retina outer nuclear layer degeneration

decreased total retina thickness

retina degeneration

abnormal a-wave shape

decreased a-wave amplitude

decreased b-wave amplitude

abnormal cone electrophysiology

abnormal rod electrophysiology

Availability

Mouse Genotype

Arl3^{Gt(OST263303)Lex}/Arl3^{Gt(OST263303)Lex}

Tg(Rho-Arl3*Q71L)#Visu/0

Arl3^{Gt(EUCJ0159b07)1.1Hmgu}/Arl3^{Gt(EUCJ0159b07)1.1Hmgu}
Tg(Rho-icre)1Ck/0 (conditional)

Arl3^{Gt(EUCJ0159b07)1.1Hmgu}/Arl3^{Gt(EUCJ0159b07)1.1Hmgu}
Tg(Six3-cre)69Frty/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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