About Help FAQ

Symbol
Name
ID

Tyk2
tyrosine kinase 2
MGI:1929470

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Increased circulating IgE level
Disease(s) Associated with TYK2	Increased circulating IgE level
immunodeficiency 35

Mouse Phenotypes		decreased macrophage nitric oxide production	impaired adaptive thermogenesis	increased circulating insulin level	increased circulating free fatty acids level	increased circulating interleukin-12 level	abnormal body temperature homeostasis	decreased energy expenditure	abnormal nitric oxide homeostasis	impaired glucose tolerance	increased cholesterol level
Availability	Mouse Genotype	decreased macrophage nitric oxide production	impaired adaptive thermogenesis	increased circulating insulin level	increased circulating free fatty acids level	increased circulating interleukin-12 level	abnormal body temperature homeostasis	decreased energy expenditure	abnormal nitric oxide homeostasis	impaired glucose tolerance	increased cholesterol level
	Tyk2^E775K/Tyk2^E775K
	Tyk2^tm1Biat/Tyk2^tm1Biat
	Tyk2^tm1Shmd/Tyk2^tm1Shmd

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23