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Symbol
Name
ID

Pus1
pseudouridine synthase 1
MGI:1929237

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Decreased activity of mitochondrial complex I	Decreased activity of mitochondrial complex IV	Increased circulating ferritin concentration	Increased circulating lactate concentration	Lactic acidosis	Exercise intolerance
Disease(s) Associated with PUS1
myopathy, lactic acidosis, and sideroblastic anemia 1

Mouse Phenotypes		impaired exercise endurance	increased circulating bilirubin level	increased circulating phosphate level
Availability	Mouse Genotype	impaired exercise endurance	increased circulating bilirubin level	increased circulating phosphate level
	Pus1^em1(IMPC)J/Pus1^em1(IMPC)J
	Pus1^tm1.1Mdf/Pus1^tm1.1Mdf

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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