Symbol
Name
ID

Htra2
HtrA serine peptidase 2
MGI:1928676

Phenotype annotations related to behavior/neurological

Darker colors indicate more annotations

Human Phenotypes	Feeding difficulties	Poor suck	Depression	Apathy	Reduced social reciprocity	Impulsivity	Agitation	Restless legs
Disease(s) Associated with HTRA2	Feeding difficulties	Poor suck	Depression	Apathy	Reduced social reciprocity	Impulsivity	Agitation	Restless legs
3-methylglutaconic aciduria type 8
Parkinson's disease

Mouse Phenotypes

abnormal behavior

lethargy

limb grasping

dystonia

tremors

ataxia

impaired balance

impaired coordination

decreased grip strength

hunched posture

abnormal stationary movement

abnormal locomotor behavior

akinesia

abnormal gait

decreased locomotor activity

bradykinesia

paralysis

no spontaneous movement

increased stereotypic behavior

seizures

Availability

Mouse Genotype

Htra2^mnd2/Htra2^mnd2

Htra2^tm1.2Hohj/Htra2^tm1.2Hohj

Htra2^tm1Jdo/Htra2^tm1Jdo

Htra2^tm1.1Hohj/Htra2^tm1.1Hohj
Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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