|
Symbol Name ID |
Sirt3
sirtuin 3 MGI:1927665 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
increased susceptibility to diet-induced obesity |
hyperglycemia |
increased circulating insulin level |
increased circulating LDL cholesterol level |
increased circulating VLDL cholesterol level |
increased circulating cholesterol level |
increased circulating triglyceride level |
increased circulating interferon-gamma level |
increased circulating interleukin-10 level |
increased circulating interleukin-12 level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
increased circulating alanine transaminase level |
increased circulating creatine kinase level |
abnormal enzyme/coenzyme level |
decreased carbon dioxide production |
decreased oxygen consumption |
insulin resistance |
abnormal lipid homeostasis |
increased liver cholesterol level |
increased liver triglyceride level |
abnormal cytokine level |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||
| Sirt3tm1.1Fwa/Sirt3tm1.1Fwa | ||||||||||||||||||||||||
| Sirt3tm1b(EUCOMM)Wtsi/Sirt3tm1b(EUCOMM)Wtsi | ||||||||||||||||||||||||
| Sirt3tm1.1Auw/Sirt3tm1.1Auw Tg(ACTA1-cre)79Jme/0 (conditional) |
* | |||||||||||||||||||||||
| Sirt3tm1.1Auw/Sirt3tm1.1Auw Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
* | |||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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