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Symbol Name ID |
Ggcx
gamma-glutamyl carboxylase MGI:1927655 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Elevated circulating hepatic transaminase concentration |
Epiphyseal stippling |
| Disease(s) Associated with GGCX | ||
| combined deficiency of vitamin K-dependent clotting factors 1 |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
decreased susceptibility to diet-induced obesity |
hypoglycemia |
abnormal circulating osteocalcin level |
decreased circulating osteocalcin level |
impaired blood coagulation |
increased bleeding time |
increased carbon dioxide production |
increased oxygen consumption |
improved glucose tolerance |
increased insulin sensitivity |
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| Availability | Mouse Genotype | |||||||||||
| Ggcxtm1Dgi/Ggcx+ | * | |||||||||||
| Ggcxtm1.1Kry/Ggcxtm1.1Kry Tg(Col1a1-cre)1Kry/0 (conditional) |
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| Ggcxtm1.1Kry/Ggcxtm1.1Kry Tg(BGLAP-cre)1Clem/0 (conditional) |
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| Ggcxtm1Sinos/Ggcxtm1Sinos Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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