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Symbol
Name
ID
Trpv4
transient receptor potential cation channel, subfamily V, member 4
MGI:1926945
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Decreased fetal movement
Fetal akinesia sequence
Urinary incontinence
Vocal cord paresis
Hoarse voice
Disease(s) Associated with TRPV4
autosomal dominant distal hereditary motor neuronopathy 8
Charcot-Marie-Tooth disease axonal type 2C
metatropic dysplasia
scapuloperoneal spinal muscular atrophy

Mouse Phenotypes
behavior/neurological phenotype
abnormal drinking behavior
decreased fluid intake
abnormal response to tactile stimuli
abnormal sensory capabilities/reflexes/nociception
increased chemical nociceptive threshold
abnormal mechanical nociception
abnormal nociception after inflammation
abnormal pain threshold
increased thermal nociceptive threshold
Availability Mouse Genotype
Trpv4tm1Msz/Trpv4tm1Msz
Trpv4tm1Rck/Trpv4tm1Rck *
Trpv4tm1.1Ldtk/Trpv4tm1.1Ldtk
Tg(KRT14-cre/ERT)20Efu/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory