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Symbol Name ID |
Kcnt1
potassium channel, subfamily T, member 1 MGI:1924627 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Depression |
Atypical behavior |
Personality disorder |
Aggressive behavior |
| Disease(s) Associated with KCNT1 | ||||
| autosomal dominant nocturnal frontal lobe epilepsy 5 |
| Mouse Phenotypes | behavior/neurological phenotype |
abnormal behavior |
increased susceptibility to pharmacologically induced seizures |
impaired contextual conditioning behavior |
impaired cued conditioning behavior |
abnormal motor learning |
decreased exploration in new environment |
decreased anxiety-related response |
decreased thigmotaxis |
increased anxiety-related response |
increased thigmotaxis |
decreased fear-related response |
decreased locomotor activity |
hyperactivity |
abnormal mechanical nociception |
abnormal nest building behavior |
seizures |
abnormal seizure response to electrical stimulation |
tonic seizures |
tonic-clonic seizures |
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| Availability | Mouse Genotype | ||||||||||||||||||||
| Kcnt1em1(IMPC)Mbp/Kcnt1em1(IMPC)Mbp | |||||||||||||||||||||
| Kcnt1em1Nju/Kcnt1em1Nju | * | ||||||||||||||||||||
| Kcnt1em1Pqt/Kcnt1em1Pqt | |||||||||||||||||||||
| Kcnt1em8Frk/Kcnt1em8Frk | * | ||||||||||||||||||||
| Kcnt1tm1.2Acsc/Kcnt1tm1.2Acsc | * | ||||||||||||||||||||
| Kcnt1tm1Dgen/Kcnt1tm1Dgen | * | ||||||||||||||||||||
| Kcnt1em1Lekk/Kcnt1+ | * | ||||||||||||||||||||
| Kcnt1em1Pqt/Kcnt1+ | * | ||||||||||||||||||||
| Kcnt1tm1.1Acsc/Kcnt1tm1.1Acsc Tg(Scn10a-cre)1Rkun/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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