|
Symbol Name ID |
Ankrd11
ankyrin repeat domain 11 MGI:1924337 |
| Darker colors indicate more annotations |
| Human Phenotypes | Low anterior hairline |
Low posterior hairline |
Brachycephaly |
Microcephaly |
Persistent open anterior fontanelle |
Round face |
Triangular face |
Pointed chin |
Long philtrum |
Tented upper lip vermilion |
Thin upper lip vermilion |
Cleft palate |
Macrodontia |
Oligodontia |
Widely-spaced maxillary central incisors |
Anteverted nares |
Underdeveloped nasal alae |
Prominent nasal bridge |
Synophrys |
Thick eyebrow |
Long palpebral fissure |
Downslanted palpebral fissures |
Telecanthus |
| Disease(s) Associated with ANKRD11 | |||||||||||||||||||||||
| KBG syndrome |
| Mouse Phenotypes | abnormal craniofacial morphology |
abnormal craniofacial bone morphology |
abnormal metopic suture morphology |
wide metopic suture |
abnormal frontonasal suture morphology |
abnormal basicranium morphology |
impaired ossification of basisphenoid bone |
increased cranium width |
abnormal neurocranium morphology |
large anterior fontanelle |
abnormal frontal bone morphology |
small frontal bone |
frontal bone hypoplasia |
short frontal bone |
enlarged parietal bone |
small parietal bone |
abnormal pterygoid bone morphology |
absent pterygoid process |
enlarged neurocranium |
abnormal mandible morphology |
small mandible |
micrognathia |
retrognathia |
abnormal nasal bone morphology |
short nasal bone |
abnormal palatine bone morphology |
domed cranium |
abnormal palatal mesenchymal cell proliferation |
abnormal palatal shelf morphology |
palatal shelves fail to meet at midline |
palatal shelf hypoplasia |
triangular face |
broad face |
midface hypoplasia |
narrow face |
short face |
abnormal snout skin morphology |
abnormal midface morphology |
cleft hard palate |
cleft palate |
decreased tongue size |
tongue hypoplasia |
short tongue |
abnormal nose morphology |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||||||
| Ankrd11Yod/Ankrd11+ | |||||||||||||||||||||||||||||||||||||||||||||
| Ankrd11tm1c(EUCOMM)Wtsi/Ankrd11tm1c(EUCOMM)Wtsi E2f1Tg(Wnt1-cre)2Sor/E2f1+ (conditional) |
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| Ankrd11tm1c(EUCOMM)Wtsi/Ankrd11+ E2f1Tg(Wnt1-cre)2Sor/E2f1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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