Symbol
Name
ID

Prss8
serine protease 8 (prostasin)
MGI:1923810

Phenotype annotations related to integument

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

integument phenotype

impaired skin barrier function

abnormal coat appearance

abnormal hair growth

short hair

sparse hair

rough coat

disheveled coat

abnormal hair shaft morphology

abnormal hair medulla

abnormal hair follicle morphology

abnormal hair follicle development

underdeveloped hair follicles

decreased hair follicle number

delayed emergence of vibrissae

abnormal vibrissa morphology

absent vibrissae

curly vibrissae

kinked vibrissae

short vibrissae

abnormal dermal layer morphology

abnormal epidermal layer morphology

abnormal epidermis stratum corneum morphology

abnormal corneocyte morphology

abnormal stratum corneum lipid matrix formation

orthokeratosis

acanthosis

dry skin

reddish skin

scaly skin

skin lesions

wrinkled skin

Availability

Mouse Genotype

Prss8^em1Bug/Prss8^em1Bug

Prss8^fr/Prss8^fr

Prss8^{Gt(IST10122F12)Tigm}/Prss8^{Gt(IST10122F12)Tigm}

Prss8^tm1.1Bug/Prss8^tm1.1Bug

Prss8^fr/Prss8^tm1.1Hum

Prss8^tm1.1Bug/Prss8^{Gt(IST10122F12)Tigm}

Tg(KRT14-Prss8)1Hum/?

Tg(KRT14-Prss8)2Hum/?

Prss8^tm1.1Hum/Prss8^tm1.2Hum
Tg(KRT14-cre)1Ipc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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