|
Symbol Name ID |
Cant1
calcium activated nucleotidase 1 MGI:1923275 |
| Darker colors indicate more annotations |
| Human Phenotypes | Microretrognathia |
Malar flattening |
Microcephaly |
Relative macrocephaly |
Short neck |
Genu varum |
Radial deviation of the 2nd finger |
Clinodactyly of the 5th finger |
Bifid distal phalanx of the thumb |
Camptodactyly of finger |
Short 1st metacarpal |
Short phalanx of finger |
Broad thumb |
Phalangeal dislocation |
Triangular shaped phalanges of the hand |
Partial duplication of the distal phalanx of the hallux |
Toe clinodactyly |
Sandal gap |
Brachydactyly |
Cutaneous syndactyly |
Hypoplasia of the capital femoral epiphysis |
Abnormal femoral neck/head morphology |
Broad femoral neck |
Coxa valga |
Coxa vara |
Monkey wrench femoral neck |
Short femoral neck |
Proximal fibular overgrowth |
Broad first metatarsal |
Short metatarsal |
Advanced tarsal ossification |
Abnormal metaphysis morphology |
Metaphyseal widening |
Radioulnar synostosis |
Short metacarpal |
Small hand |
Flat acetabular roof |
Hip dislocation |
Patellar dislocation |
Genu recurvatum |
Knee dislocation |
Advanced ossification of carpal bones |
Elbow dislocation |
Joint hypermobility |
Accelerated skeletal maturation |
Epiphyseal dysplasia |
Flattened epiphysis |
Short long bone |
Short clavicles |
Bell-shaped thorax |
Pectus carinatum |
Pectus excavatum |
Narrow chest |
Hyperlordosis |
Lumbar hyperlordosis |
Kyphosis |
Scoliosis |
Platyspondyly |
Vertebral wedging |
Osteoporosis |
Osteoarthritis |
Joint dislocation |
Radial head subluxation |
| Disease(s) Associated with CANT1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Desbuquois dysplasia | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| multiple epiphyseal dysplasia 7 |
| Mouse Phenotypes | increased chondrocyte apoptosis |
increased chondrocyte proliferation |
abnormal phalanx morphology |
decreased diameter of femur |
decreased diameter of tibia |
abnormal long bone epiphyseal plate morphology |
abnormal long bone epiphyseal plate proliferative zone |
abnormal long bone hypertrophic chondrocyte zone |
abnormal ilium morphology |
short ilium |
kyphosis |
abnormal cartilage morphology |
abnormal chondrocyte morphology |
chondrodystrophy |
abnormal endochondral bone ossification |
delayed endochondral bone ossification |
abnormal chondrocyte physiology |
|
| Availability | Mouse Genotype | |||||||||||||||||
| Cant1tm1.1Aros/Cant1tm1.1Aros | ||||||||||||||||||
| Cant1tm1.2Aros/Cant1tm1.2Aros | ||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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