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Symbol
Name
ID
Med23
mediator complex subunit 23
MGI:1917458
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Microcephaly
Disease(s) Associated with MED23
autosomal recessive intellectual developmental disorder 18

Mouse Phenotypes
abnormal cranium morphology
abnormal Meckel's cartilage morphology
Meckel's cartilage hypoplasia
abnormal cranial cartilage development
frontal bone hypoplasia
temporal bone hypoplasia
small lower incisors
abnormal tooth development
growth retardation of incisors
growth retardation of molars
mandibular condyloid process hypoplasia
absent mandibular symphysis
small mandible
mandible hypoplasia
micrognathia
absent palatine bone
abnormal nasal cartilage morphology
nasal cartilage hypoplasia
decreased bone mineral content
Availability Mouse Genotype
Med23em1(IMPC)Wtsi/Med23+
Med23tm1c(KOMP)Wtsi/Med23tm1c(KOMP)Wtsi
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory