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Symbol
Name
ID
Rnf146
ring finger protein 146
MGI:1915281
Phenotype annotations related to skeleton
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
skeleton phenotype
increased bone marrow adipose tissue amount
impaired osteoblast differentiation
abnormal osteoclast differentiation
decreased osteoblast proliferation
large anterior fontanelle
large posterior fontanelle
abnormal alveolar process morphology
abnormal ameloblast differentiation
increased osteoclast cell number
abnormal limb long bone morphology
clavicle hypoplasia
abnormal rib morphology
decreased bone mineral density
decreased compact bone volume
decreased trabecular bone volume
abnormal compact bone morphology
decreased compact bone thickness
decreased osteoblast cell number
decreased bone trabecula number
increased bone trabecular spacing
decreased trabecular bone mass
decreased bone mineralization
abnormal endochondral bone ossification
abnormal intramembranous bone ossification
decreased bone ossification
Availability Mouse Genotype
Rnf146tm1.1Rtpl/Rnf146tm1.1Rtpl
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)
*
Rnf146tm1.1Rtpl/Rnf146tm1.1Rtpl
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory