Symbol
Name
ID

Prg4
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
MGI:1891344

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes

Camptodactyly of finger

Congenital finger flexion contractures

Camptodactyly of toe

Flattened femoral head

Coxa vara

Short femoral neck

Flattened metatarsal heads

Flattened metacarpal heads

Knee osteoarthritis

Osteoarthritis of the elbow

Wrist flexion contracture

Wrist swelling

Generalized morning stiffness

Lumbar hyperlordosis

Osteoporosis

Bone cyst

Synovial lining hyperplasia

Arthritis

Arthropathy

Polyarticular arthropathy

Disease(s) Associated with PRG4

camptodactyly-arthropathy-coxa vara-pericarditis syndrome

Mouse Phenotypes		joint swelling	abnormal long bone epiphyseal plate morphology	decreased chondrocyte number	abnormal articular cartilage morphology	abnormal joint morphology	calcified joint
Availability	Mouse Genotype	joint swelling	abnormal long bone epiphyseal plate morphology	decreased chondrocyte number	abnormal articular cartilage morphology	abnormal joint morphology	calcified joint
	Prg4^{em1(IMPC)Ccpcz}/Prg4^{em1(IMPC)Ccpcz}
	Prg4^{tm1(GFP/cre/ERT2)Abl}/Prg4^{tm1(GFP/cre/ERT2)Abl}
	Prg4^tm1Mawa/Prg4^tm1Mawa

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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