About Help FAQ

Symbol
Name
ID

Otof
otoferlin
MGI:1891247

Phenotype annotations related to hearing/vestibular/ear

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Absence of acoustic reflex	Sensorineural hearing impairment
Disease(s) Associated with OTOF	Absence of acoustic reflex	Sensorineural hearing impairment
autosomal recessive nonsyndromic deafness 9

Mouse Phenotypes		hearing/vestibular/ear phenotype	abnormal cochlear hair cell stereociliary bundle morphology	abnormal cochlear inner hair cell morphology	abnormal inner hair cell synaptic ribbon morphology	abnormal cochlear inner hair cell physiology	abnormal hearing electrophysiology	increased or absent threshold for auditory brainstem response	deafness
Availability	Mouse Genotype	hearing/vestibular/ear phenotype	abnormal cochlear hair cell stereociliary bundle morphology	abnormal cochlear inner hair cell morphology	abnormal inner hair cell synaptic ribbon morphology	abnormal cochlear inner hair cell physiology	abnormal hearing electrophysiology		deafness
	Otof^deaf5Jcs/Otof^deaf5Jcs	*
	Otof^pga/Otof^pga
	Otof^tm1.1Erei/Otof^tm1.1Erei
	Otof^tm1Ugds/Otof^tm1Ugds	*
	Otof^deaf5Jcs/Otof⁺	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23