|
Symbol Name ID |
Plin1
perilipin 1 MGI:1890505 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Hypertriglyceridemia |
Decreased resting energy expenditure |
Insulin-resistant diabetes mellitus |
Insulin-resistant diabetes mellitus at puberty |
Hyperinsulinemia |
Insulin resistance |
Hepatic steatosis |
Abnormal circulating hormone concentration |
| Disease(s) Associated with PLIN1 | ||||||||
| familial partial lipodystrophy type 4 | ||||||||
| obesity |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
decreased susceptibility to diet-induced obesity |
impaired adaptive thermogenesis |
abnormal blood homeostasis |
increased circulating insulin level |
decreased circulating leptin level |
increased circulating leptin level |
abnormal circulating ketone body level |
abnormal circulating free fatty acids level |
abnormal body temperature homeostasis |
increased oxygen consumption |
abnormal glucose homeostasis |
impaired glucose tolerance |
abnormal glycerol level |
abnormal lipolysis |
enhanced lipolysis |
impaired lipolysis |
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| Availability | Mouse Genotype | |||||||||||||||||
| Plin1tm1Asg/Plin1tm1Asg | * | |||||||||||||||||
| Plin1tm1Asg/Plin1tm1Asg Tg(Fabp4-Plin*)1Asg/0 |
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| Plin1tm1Cdl/Plin1tm1Cdl | ||||||||||||||||||
| Plin1tm1Chan/Plin1tm1Chan | ||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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