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Symbol
Name
ID
Il21
interleukin 21
MGI:1890474
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Decreased circulating IgA level
Increased circulating IgE level
Decreased circulating IgG level
Chronic partially decreased circulating IgG1
Chronic (near) absent circulating IgG4
Decreased circulating total IgG
Chronic decreased circulating total IgG
Decreased circulating total IgM
Decreased circulating antibody level
Reduced isohemagglutinin level
Decreased specific antibody response to vaccination
Complete or near-complete absence of specific antibody response to unconjugated pneumococcus vaccine
Partial absence of specific antibody response to unconjugated pneumococcus vaccine
Complete or near-complete absence of specific antibody response to tetanus vaccine
Decreased specific pneumococcal antibody level
Impaired T cell function
Elevated hepatic transaminase
Hypoglycemia
Type I diabetes mellitus
Fever
Macroscopic hematuria
Nephrotic range proteinuria
Decreased response to growth hormone stimulation test
Disease(s) Associated with IL21
common variable immunodeficiency

Mouse Phenotypes
abnormal interleukin level
Availability Mouse Genotype
Il21tm1Lex/Il21tm1Lex

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/28/2022
MGI 6.20
The Jackson Laboratory