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Symbol
Name
ID
Foxo1
forkhead box O1
MGI:1890077
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
homeostasis/metabolism phenotype
pericardial effusion
increased susceptibility to diet-induced obesity
increased circulating glucose level
hyperglycemia
decreased circulating insulin level
increased circulating insulin level
increased circulating HDL cholesterol level
decreased circulating cholesterol level
increased circulating cholesterol level
decreased circulating free fatty acid level
decreased circulating triglyceride level
decreased circulating VLDL triglyceride level
increased circulating triglyceride level
decreased circulating tumor necrosis factor level
decreased energy expenditure
decreased carbon dioxide production
decreased respiratory quotient
abnormal glucose homeostasis
abnormal gluconeogenesis
impaired glucose tolerance
improved glucose tolerance
decreased glycogen level
increased insulin sensitivity
insulin resistance
abnormal lipid homeostasis
decreased liver cholesterol level
decreased liver triglyceride level
Availability Mouse Genotype
Foxo1tm1Tf/Foxo1tm1Tf
Foxo1tm2.1Dac/Foxo1tm2.1Dac
Foxo1tm1Whb/Foxo1+
Tg(Ttr-Foxo1)305Dac/0
Tg(Ttr-Foxo1)307Dac/0
Foxo1tm1Rdp/Foxo1tm1Rdp
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
Foxo1tm1Rdp/Foxo1tm1.1Rdp
Tg(Col1a1-cre)1Kry/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/12/2019
MGI 6.13
The Jackson Laboratory