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Symbol
Name
ID

Foxe3
forkhead box E3
MGI:1353569

Phenotype annotations related to vision/eye

Darker colors indicate more annotations

Human Phenotypes	Abnormality iris morphology	Abnormal iris pigmentation	Iris flocculi	Hypertelorism
Disease(s) Associated with FOXE3
thoracic aortic aneurysm

Mouse Phenotypes

abnormal pupillary reflex

corneal vascularization

abnormal eye morphology

abnormal anterior eye segment morphology

abnormal iridocorneal angle

abnormal canal of Schlemm morphology

absent trabecular meshwork

abnormal ciliary body morphology

abnormal iris morphology

small pupil

iris hypoplasia

anterior iris synechia

abnormal cornea morphology

abnormal corneal endothelium morphology

absent corneal endothelium

abnormal corneal epithelium morphology

decreased corneal epithelium thickness

abnormal corneal stroma morphology

corneal opacity

corneal-lenticular stalk

fused cornea and lens

abnormal eye anterior chamber morphology

abnormal lens morphology

abnormal lens development

abnormal lens induction

abnormal lens vesicle development

lens vacuoles

abnormal lens epithelium morphology

abnormal lens fiber morphology

disorganized secondary lens fibers

cataract

cortical cataract

developmental cataract

anterior polar cataract

small lens

microphthalmia

eyelids fail to open

retina fold

anophthalmia

Availability

Mouse Genotype

Foxe3^dyl/Foxe3^dyl

Foxe3^em1(IMPC)Mbp/Foxe3^em1(IMPC)Mbp

Foxe3^rct/Foxe3^rct

Foxe3^tm1Mjam/Foxe3^tm1Mjam

Foxe3^tm1Pca/Foxe3^tm1Pca

Foxe3^dyl/Foxe3⁺

Foxe3^dyl/Foxe3^tm1Pca

Foxe3^tm1Pca/Foxe3⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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