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Symbol Name ID |
Esr1
estrogen receptor 1 (alpha) MGI:1352467 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Osteoporosis |
Gout |
| Disease(s) Associated with ESR1 | ||
| coronary artery disease | ||
| osteoporosis |
| Mouse Phenotypes | skeleton phenotype |
increased osteoclast cell number |
abnormal osteoclast physiology |
short ulna |
decreased femoral compact bone area |
short femur |
short tibia |
abnormal long bone epiphyseal plate morphology |
decreased long bone epiphyseal plate size |
decreased length of long bones |
abnormal vertebrae morphology |
abnormal bone structure |
decreased bone mineral content |
decreased areal bone mineral density |
decreased bone mineral density of femur |
abnormal volumetric bone mineral density |
decreased volumetric bone mineral density |
increased volumetric bone mineral density |
increased bone mineral density |
decreased compact bone area |
increased compact bone area |
decreased compact bone mass |
decreased compact bone thickness |
decreased osteoblast cell number |
abnormal trabecular bone morphology |
decreased bone mass |
osteoporosis |
abnormal skeleton development |
abnormal skeleton physiology |
abnormal bone mineralization |
decreased bone mineralization |
increased bone mineralization |
decreased bone ossification |
increased bone ossification |
increased bone resorption |
decreased bone strength |
abnormal chondrocyte physiology |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||
| Esr1tm1.1Mma/Esr1tm1.1Mma | ||||||||||||||||||||||||||||||||||||||
| Esr1tm1.1Ohl/Esr1tm1.1Ohl | ||||||||||||||||||||||||||||||||||||||
| Esr1tm1Arnal/Esr1tm1Arnal | ||||||||||||||||||||||||||||||||||||||
| Esr1tm1Ksk/Esr1tm1Ksk | * | |||||||||||||||||||||||||||||||||||||
| Esr1tm4.2Ksk/Esr1tm4.2Ksk | ||||||||||||||||||||||||||||||||||||||
| Esr1tm1.1Lja/Esr1+ | ||||||||||||||||||||||||||||||||||||||
| Esr1tm1.1Lja/Esr1tm1.1Mma | ||||||||||||||||||||||||||||||||||||||
| Esr1tm1.1Scma/Esr1tm1.1Scma Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Ctsktm1(cre)Ska/Ctsk+ Esr1tm1Mma/Esr1tm1Mma (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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