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Symbol
Name
ID

Esr1
estrogen receptor 1 (alpha)
MGI:1352467

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Photophobia	Phonophobia	Chest pain
Disease(s) Associated with ESR1	Photophobia	Phonophobia	Chest pain
coronary artery disease
migraine

Mouse Phenotypes

behavior/neurological phenotype

impaired passive avoidance behavior

decreased aggression

decreased aggression towards mice

decreased aggression towards male mice

increased aggression towards mice

increased aggression towards female mice

hyporesponsive to tactile stimuli

decreased vertical activity

increased vertical activity

hyperactivity

abnormal nociception after inflammation

abnormal maternal nurturing

abnormal pup retrieval

pup cannibalization

reduced male mating frequency

abnormal mating receptivity

abnormal social investigation

Availability

Mouse Genotype

Esr1^tm1.1Mma/Esr1^tm1.1Mma

*

Esr1^tm1Ksk/Esr1^tm1Ksk

*

Esr1^{tm1.1(cre)And}/Esr1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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