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Symbol
Name
ID
Nr1h3
nuclear receptor subfamily 1, group H, member 3
MGI:1352462
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
homeostasis/metabolism phenotype
abnormal cellular cholesterol metabolism
decreased circulating testosterone level
increased circulating estradiol level
decreased circulating luteinizing hormone level
increased circulating LDL cholesterol level
increased circulating cholesterol level
decreased circulating triglyceride level
increased circulating alanine transaminase level
increased circulating aspartate transaminase level
abnormal lipid homeostasis
abnormal bile salt homeostasis
abnormal cholesterol homeostasis
increased liver cholesterol level
increased liver triglyceride level
decreased physiological sensitivity to xenobiotic
Availability Mouse Genotype
Nr1h3tm1.1(KOMP)Vlcg/Nr1h3tm1.1(KOMP)Vlcg
Nr1h3tm1.1Gstr/Nr1h3tm1.1Gstr
Nr1h3tm1.1Nph/Nr1h3tm1.1Nph *
Nr1h3tm1Dgen/Nr1h3tm1Dgen
Nr1h3tm1Djm/Nr1h3tm1Djm *
Tg(Fabp1-Nr1h3)#Wexi/?
Nr1h3tm1.1Djm/Nr1h3tm1.1Djm
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory