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Symbol
Name
ID
Nr4a2
nuclear receptor subfamily 4, group A, member 2
MGI:1352456
Phenotype annotations related to behavior/neurological
Darker colors indicate more annotations
Human Phenotypes
Depression
Apathy
Reduced social reciprocity
Impulsivity
Agitation
Restless legs
Disease(s) Associated with NR4A2
Parkinson's disease

Mouse Phenotypes
enhanced behavioral response to addictive substance
enhanced behavioral response to xenobiotic
impaired passive avoidance behavior
abnormal suckling behavior
behavioral despair
abnormal motor capabilities/coordination/movement
impaired righting response
impaired coordination
abnormal locomotor activation
akinesia
decreased vertical activity
decreased locomotor activity
increased locomotor activity
hyperactivity
increased stereotypic behavior
Availability Mouse Genotype
Nr4a2tm1Omc/Nr4a2tm1Omc
Nr4a2tm1Tpe/Nr4a2tm1Tpe
Nr4a2tm1Omc/Nr4a2+
Nr4a2tm1Tpe/Nr4a2+
Nr4a2tm1.1Pcn/Nr4a2tm1.1Pcn
Slc6a3tm1(cre)Lrsn/Slc6a3tm1(cre)Lrsn  (conditional)
Nr4a2tm1.1Pcn/Nr4a2tm1.1Pcn  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory