Symbol
Name
ID

Abcc6
ATP-binding cassette, sub-family C member 6
MGI:1351634

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes

Abnormal calcification of the carpal bones

Hypophosphatemic rickets

Increased LDL cholesterol concentration

Hypercholesterolemia

Hypertriglyceridemia

Elevated alkaline phosphatase of bone origin

Glucose intolerance

Diabetes mellitus

Type II diabetes mellitus

Impaired glucose tolerance

Edema

Hydrops fetalis

Peau d'orange

Fever

Hyperphosphaturia

Myocardial calcification

Calcification of the aorta

Abdominal aortic calcification

Coronary artery calcification

Arterial calcification

Carotid artery calcification

Generalized arterial calcification

Medial calcification of large arteries

Medial calcification of medium-sized arteries

Ascites

Hepatic calcification

Pancreatic calcification

Calcification of the auricular cartilage

Adrenal calcification

Ectopic calcification

Cerebral calcification

Calcification of falx cerebri

Periarticular calcification

Disease(s) Associated with ABCC6

arterial calcification of infancy

coronary artery disease

pseudoxanthoma elasticum

Mouse Phenotypes		increased circulating creatinine level	decreased circulating HDL cholesterol level	calcinosis
Availability	Mouse Genotype	increased circulating creatinine level	decreased circulating HDL cholesterol level	calcinosis
	Abcc6^tm1Aabb/Abcc6^tm1Aabb
	Abcc6^tm1Jfk/Abcc6^tm1Jfk
	Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Tg(CMV-cre)1Cgn/? (conditional)
	Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} E2f1^{Tg(Wnt1-cre)2Sor}/? (conditional)
	Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} E2f1^{Tg(Wnt1-cre)2Sor}/? Speer6-ps1^{Tg(Alb-cre)21Mgn}/? (conditional)
	Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Speer6-ps1^{Tg(Alb-cre)21Mgn}/? (conditional)
	Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Speer6-ps1^{Tg(Alb-cre)21Mgn}/? Tg(Cdx1-cre)23Kem/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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