Symbol
Name
ID

Abcb11
ATP-binding cassette, sub-family B member 11
MGI:1351619

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Conjugated hyperbilirubinemia	Elevated circulating alkaline phosphatase concentration
Disease(s) Associated with ABCB11	Conjugated hyperbilirubinemia	Elevated circulating alkaline phosphatase concentration
benign recurrent intrahepatic cholestasis 2
progressive familial intrahepatic cholestasis 2

Mouse Phenotypes

increased circulating bilirubin level

increased circulating fructosamine level

decreased circulating triglyceride level

increased circulating potassium level

increased circulating alanine transaminase level

increased circulating alkaline phosphatase level

increased circulating amylase level

increased circulating aspartate transaminase level

increased circulating unsaturated transferrin level

decreased liver glycogen level

abnormal bile salt level

increased bile salt level

increased cholesterol level

abnormal phospholipid level

Availability

Mouse Genotype

Abcb11^{tm1a(EUCOMM)Hmgu}/Abcb11^{tm1a(EUCOMM)Hmgu}

Abcb11^tm1Wng/Abcb11^tm1Wng

Abcb11^{tm1b(EUCOMM)Hmgu}/Abcb11⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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