Symbol
Name
ID

Casr
calcium-sensing receptor
MGI:1351351

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes

Hypercalcemia

Hypocalcemia

Hypermagnesemia

Hypomagnesemia

Hypokalemia

Hyperphosphatemia

Hypophosphatemia

Hypermagnesiuria

Hyperphosphaturia

Hypercalciuria

Hypocalciuria

Hyperoxaluria

Decreased circulating parathyroid hormone level

Elevated circulating parathyroid hormone level

Chondrocalcinosis

Basal ganglia calcification

Disease(s) Associated with CASR

autosomal dominant hypocalcemia

autosomal dominant hypocalcemia 1

calcium oxalate nephrolithiasis

familial hypocalciuric hypercalcemia 1

hyperparathyroidism

Mouse Phenotypes

decreased circulating parathyroid hormone level

increased circulating parathyroid hormone level

decreased circulating calcium level

increased circulating calcium level

increased circulating magnesium level

decreased circulating phosphate level

increased circulating phosphate level

dehydration

edema

calcinosis

decreased urine calcium level

increased urine calcium level

decreased urine phosphate level

Availability

Mouse Genotype

Casr^BCH002/Casr^BCH002

Casr^BCH003/Casr^BCH003

Casr^BCH004/Casr^BCH004

Casr^BCH007/Casr^BCH007

Casr^BCH011/Casr^BCH011

Casr^BCH013/Casr^BCH013

Casr^Nuf/Casr^Nuf

Casr^tm1Ces/Casr^tm1Ces

Casr^Nuf/Casr⁺

Casr^{tm1b(KOMP)Mbp}/Casr⁺

Casr^tm1Ces/Casr⁺

Casr^tm1Wch/Casr^tm1Wch
Tg(PTH-cre)4167Slib/0 (conditional)

Casr^tm1Wch/Casr⁺
Tg(PTH-cre)4167Slib/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23