Symbol
Name
ID

Triobp
TRIO and F-actin binding protein
MGI:1349410

Phenotype annotations related to hearing/vestibular/ear

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Severe sensorineural hearing impairment
Disease(s) Associated with TRIOBP	Severe sensorineural hearing impairment
autosomal recessive nonsyndromic deafness 28

Mouse Phenotypes

hearing/vestibular/ear phenotype

abnormal cochlear hair cell development

abnormal inner hair cell stereociliary bundle morphology

fused inner hair cell stereocilia

abnormal outer hair cell stereociliary bundle morphology

fused outer hair cell stereocilia

decreased cochlear hair cell stereocilia number

abnormal cochlear hair cell physiology

abnormal auditory brainstem response

increased or absent threshold for auditory brainstem response

deafness

Availability

Mouse Genotype

Triobp^em1(IMPC)J/Triobp^em1(IMPC)J

Triobp^tm1Tbf/Triobp^tm1Tbf

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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