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Symbol
Name
ID

Fto
FTO alpha-ketoglutarate dependent dioxygenase
MGI:1347093

Phenotype annotations related to growth/size/body

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Increased waist to hip ratio	Obesity
Disease(s) Associated with FTO	Increased waist to hip ratio	Obesity
coronary artery disease
obesity
type 2 diabetes mellitus

Mouse Phenotypes		growth/size/body region phenotype	decreased lean body mass	increased lean body mass	decreased body weight	cachexia	increased body weight	decreased body length	decreased susceptibility to diet-induced obesity	increased susceptibility to diet-induced obesity	postnatal growth retardation
Availability	Mouse Genotype	growth/size/body region phenotype	decreased lean body mass	increased lean body mass	decreased body weight	cachexia	increased body weight	decreased body length	decreased susceptibility to diet-induced obesity	increased susceptibility to diet-induced obesity	postnatal growth retardation
	Fto^{Gt(RRZ624)Byg}/Fto^{Gt(RRZ624)Byg}	*
	Fto^I367F/Fto^I367F
	Fto^tm1.2Pzg/Fto^tm1.2Pzg
	Fto^tm1.2Rdc/Fto^tm1.2Rdc
	Fto^tm1.3Pzg/Fto^tm1.3Pzg
	Fto^{tm1a(EUCOMM)Wtsi}/Fto^{tm1a(EUCOMM)Wtsi}
	Fto^tm1Urt/Fto^tm1Urt
	Gt(ROSA)26Sor^{tm1.1(CAG-Fto)Rdc}/Gt(ROSA)26Sor^{tm1.1(CAG-Fto)Rdc}
	Fto^I367F/Fto⁺
	Fto^tm1Urt/Fto⁺
	Gt(ROSA)26Sor^{tm1.1(CAG-Fto)Rdc}/Gt(ROSA)26Sor⁺
	Fto^tm1.1Pzg/Fto^tm1.1Pzg Tg(Nes-cre)1Kln/0 (conditional)
	Fto^tm1.1Rdc/Fto^tm1.1Rdc (conditional)
	Fto^tm1.1Rdc/Fto^tm1.1Rdc Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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