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Symbol
Name
ID

Clcn7
chloride channel, voltage-sensitive 7
MGI:1347048

Phenotype annotations related to cellular

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Elevated serum acid phosphatase
Disease(s) Associated with CLCN7	Elevated serum acid phosphatase
autosomal dominant osteopetrosis 2

Mouse Phenotypes		cellular phenotype	abnormal lysosome morphology	accumulation of giant lysosomes in kidney/renal tubule cells	abnormal autophagy	enhanced autophagy	abnormal lysosome physiology	lysosomal protein accumulation
Availability	Mouse Genotype	cellular phenotype	abnormal lysosome morphology		abnormal autophagy	enhanced autophagy	abnormal lysosome physiology	lysosomal protein accumulation
	Clcn7^tm1.1Lex/Clcn7^tm1.1Lex
	Clcn7^tm2Tjj/Clcn7^tm2Tjj
	Clcn7^tm4.1Tjj/Clcn7^tm4.1Tjj
	Clcn7^tm5.1Tjj/Clcn7^tm5.1Tjj	*
	Clcn7^tm3.1Tjj/Clcn7^tm3.1Tjj Emx1^{tm1.1(cre)Ito}/Emx1⁺ (conditional)
	Clcn7^tm3.1Tjj/Clcn7^tm3.1Tjj Tg(APOE-cre)VITew/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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