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Symbol Name ID |
Map3k7
mitogen-activated protein kinase kinase kinase 7 MGI:1346877 |
| Darker colors indicate more annotations |
| Human Phenotypes | Low anterior hairline |
Full cheeks |
Pointed chin |
Short chin |
Deep philtrum |
Short philtrum |
Bifid uvula |
Cleft palate |
High palate |
Pierre-Robin sequence |
Broad nasal tip |
Depressed nasal bridge |
Wide nasal bridge |
Thick eyebrow |
Downslanted palpebral fissures |
Prominent supraorbital ridges |
| Disease(s) Associated with MAP3K7 | ||||||||||||||||
| frontometaphyseal dysplasia 2 |
| Mouse Phenotypes | abnormal pharyngeal arch artery morphology |
abnormal craniofacial morphology |
decreased cranium height |
short mandible |
short maxilla |
abnormal secondary palate development |
failure of palatal shelf elevation |
palatal shelf hypoplasia |
cleft secondary palate |
periorbital edema |
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| Availability | Mouse Genotype | ||||||||||
| Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg | |||||||||||
| Map3k7tm1Mis/Map3k7tm1Mis H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Tg(CAG-Map3k7*K63W)1232Mds/0 Tg(Myh6-cre)2182Mds/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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