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Symbol
Name
ID

Mthfd1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
MGI:1342005

Phenotype annotations related to growth/size/body

Darker colors indicate more annotations

Human Phenotypes	Broad neck	Thickened nuchal skin fold	Redundant neck skin	Short neck	Inguinal hernia	Umbilical hernia	Delayed puberty	Short stature	Obesity
Disease(s) Associated with MTHFD1	Broad neck	Thickened nuchal skin fold	Redundant neck skin	Short neck	Inguinal hernia	Umbilical hernia	Delayed puberty	Short stature	Obesity
developmental cardiac valvular defect
Down syndrome

Mouse Phenotypes		embryonic growth retardation	decreased embryo size	increased body weight
Availability	Mouse Genotype	embryonic growth retardation	decreased embryo size	increased body weight
	Mthfd1^tm1.1Rzn/Mthfd1^tm1.1Rzn
	Mthfd1^Gt(XB175)Byg/Mthfd1⁺
	Mthfd1^tm1.1Rzn/Mthfd1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23