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Symbol
Name
ID
Stk11
serine/threonine kinase 11
MGI:1341870
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abnormality of metabolism/homeostasis
Increased level of L-fucose in urine
Disease(s) Associated with STK11
pancreatic carcinoma
testicular germ cell cancer

Mouse Phenotypes
homeostasis/metabolism phenotype
abnormal circulating glucose level
increased circulating glucose level
increased circulating interleukin-10 level
abnormal gluconeogenesis
impaired glucose tolerance
improved glucose tolerance
abnormal glycogen homeostasis
insulin resistance
abnormal lipid homeostasis
increased incidence of tumors by chemical induction
Availability Mouse Genotype
Stk11tm1.1Arte/Stk11tm1.1Arte *
Stk11tm1Keis/Stk11tm1Keis *
Stk11tm1.2Rdp/Stk11+
Stk11tm1.1Rdp/Stk11tm1.1Rdp  (conditional) *
Stk11tm1.1Rdp/Stk11tm1.1Rdp
Tg(Pdx1-cre)89.1Dam/0  (conditional)
Stk11tm1Keis/Stk11tm1Keis
Tg(Pomc1-cre)1Gsb/0  (conditional)
*
Stk11tm1Keis/Stk11tm1Keis
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory