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Symbol Name ID |
Smc3
structural maintenance of chromosomes 3 MGI:1339795 |
| Darker colors indicate more annotations |
| Human Phenotypes | Low anterior hairline |
Frontal bossing |
Brachycephaly |
Plagiocephaly |
Micrognathia |
Primary microcephaly |
Secondary microcephaly |
Delayed closure of the anterior fontanelle |
Facial asymmetry |
Flat face |
Long philtrum |
Smooth philtrum |
Thin upper lip vermilion |
Thin vermilion border |
Cleft palate |
High palate |
Downturned corners of mouth |
Microdontia |
Anteverted nares |
Bulbous nose |
Depressed nasal bridge |
Prominent nasal bridge |
Highly arched eyebrow |
Laterally extended eyebrow |
Synophrys |
Thick eyebrow |
Long eyelashes |
Hooded eyelid |
Nasolacrimal duct obstruction |
| Disease(s) Associated with SMC3 | |||||||||||||||||||||||||||||
| Cornelia de Lange syndrome 3 |
| Mouse Phenotypes | abnormal craniofacial morphology |
small cranium |
cleft palate |
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| Availability | Mouse Genotype | |||
| Smc3tm1a(EUCOMM)Wtsi/Smc3+ | ||||
| Smc3tm1.1Toshi/Smc3tm1.1Toshi H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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