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Symbol
Name
ID 		St14
suppression of tumorigenicity 14 (colon carcinoma)
MGI:1338881
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Sparse eyebrow
Curly eyelashes
Sparse eyelashes
Sparse hair
Sparse body hair
Pili torti
Brittle hair
Curly hair
Abnormality of the nail
Hypohidrosis
Hyperkeratosis
Congenital ichthyosiform erythroderma
Pruritus
Disease(s) Associated with ST14
autosomal recessive congenital ichthyosis 11

Mouse Phenotypes
abnormal keratinocyte differentiation
impaired skin barrier function
alopecia
abnormal hair shaft morphology
abnormal hair follicle morphology
underdeveloped hair follicles
abnormal piliary canal morphology
decreased hair follicle number
abnormal vibrissa follicle morphology
absent vibrissae
abnormal epidermis stratum corneum morphology
abnormal corneocyte morphology
enlarged corneocyte envelope
abnormal stratum corneum lipid matrix formation
hyperkeratosis
impaired stratum corneum desquamation
abnormal epidermis stratum granulosum morphology
acanthosis
thick epidermis
abnormal skin appearance
dry skin
pallor
reddish skin
scaly skin
shiny skin
wrinkled skin
skin fibrosis
Availability Mouse Genotype
St14Gt(XM184)Byg/St14Gt(XM184)Byg
St14tm1.1(KOMP)Vlcg/St14tm1.1(KOMP)Vlcg
St14tm1Bug/St14tm1Bug
St14tm2Bug/St14tm2Bug
St14Gt(RST485)Byg/St14+
St14Gt(XM184)Byg/St14+
St14tm2Bug/St14tm3Bug
Tg(CAG-cre/Esr1*)5Amc/0  (conditional)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory