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Symbol
Name
ID

Aire
autoimmune regulator
MGI:1338803

Phenotype annotations related to vision/eye

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Keratoconjunctivitis	Cataract	Pigmentary retinopathy	Perifoveal ring of hyperautofluorescence	Iridocyclitis	Reduced visual acuity	Constriction of peripheral visual field
Disease(s) Associated with AIRE
autoimmune polyendocrine syndrome type 1

Mouse Phenotypes		lacrimal gland inflammation	eye inflammation	vitreous body inflammation	increased incidence of corneal inflammation	uveitis	abnormal eye morphology	abnormal retina morphology	retina degeneration	decreased tear production
Availability	Mouse Genotype	lacrimal gland inflammation	eye inflammation	vitreous body inflammation	increased incidence of corneal inflammation	uveitis	abnormal eye morphology	abnormal retina morphology	retina degeneration	decreased tear production
	Aire^{tm1.1(NCOM)Mfgc}/Aire^{tm1.1(NCOM)Mfgc}
	Aire^tm1.1Doi/Aire^tm1.1Doi				!				!
	Aire^tm1Mand/Aire^tm1Mand
	Aire^tm1Mmat/Aire^tm1Mmat
	Aire^tm1Ptsn/Aire^tm1Ptsn
	Aire^tm1Mand/Aire⁺
	Aire^tm1Mand/Aire^tm1.1Doi

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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