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Symbol
Name
ID
Irs4
insulin receptor substrate 4
MGI:1338009
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Decreased circulating free T4 concentration
Inappropriately normal thyroid-stimulating hormone level
Disease(s) Associated with IRS4
congenital nongoitrous hypothyroidism 9

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased circulating glucose level
increased circulating glucose level
abnormal glucose tolerance
impaired glucose tolerance
Availability Mouse Genotype
Irs4tm1Lhd/Irs4tm1Lhd *
Irs4tm1.1Mfw/Y *
Irs4tm1Lhd/Y

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory