|
Symbol Name ID |
Lig4
ligase IV, DNA, ATP-dependent MGI:1335098 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Hypercalcemia |
Elevated circulating creatinine concentration |
Hyperproteinemia |
Elevated circulating hepatic transaminase concentration |
Diabetes mellitus |
Type II diabetes mellitus |
Pleural effusion |
Abnormality of vitamin B12 metabolism |
Amyloidosis |
| Disease(s) Associated with LIG4 | |||||||||||||
| DNA ligase IV deficiency | |||||||||||||
| multiple myeloma | |||||||||||||
| pancreatic cancer |
| Mouse Phenotypes | abnormal DNA repair |
abnormal double-strand DNA break repair |
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| Availability | Mouse Genotype | ||
| Lig4tiny/Lig4tiny | |||
| Lig4tm1Pmc/Lig4tm1Pmc Tg(Nes-cre)1Kln/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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