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Symbol
Name
ID
Lig4
ligase IV, DNA, ATP-dependent
MGI:1335098
Phenotype annotations related to growth/size/body
Darker colors indicate more annotations
Human Phenotypes
Splenomegaly
Hepatosplenomegaly
Peritoneal abscess
Tall stature
Failure to thrive
Small for gestational age
Weight loss
Disease(s) Associated with LIG4
DNA ligase IV deficiency
multiple myeloma
pancreatic cancer

Mouse Phenotypes
decreased body weight
microcephaly
decreased body size
postnatal growth retardation
decreased fetal size
Availability Mouse Genotype
Lig4tiny/Lig4tiny
Lig4tm1Fwa/Lig4tm1Fwa
Lig4tm2.1Fwa/Lig4tm2.1Fwa
Lig4tm1Pmc/Lig4tm1Pmc
Tg(Nes-cre)1Kln/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory