Symbol
Name
ID

Inppl1
inositol polyphosphate phosphatase-like 1
MGI:1333787

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Decreased resting energy expenditure	Type II diabetes mellitus	Insulin resistance
Disease(s) Associated with INPPL1	Decreased resting energy expenditure	Type II diabetes mellitus	Insulin resistance
obesity
type 2 diabetes mellitus

Mouse Phenotypes

decreased susceptibility to diet-induced obesity

hypoglycemia

decreased circulating insulin level

decreased circulating leptin level

decreased circulating cholesterol level

decreased circulating free fatty acids level

decreased circulating triglyceride level

cyanosis

abnormal gluconeogenesis

improved glucose tolerance

abnormal glycogen homeostasis

increased insulin sensitivity

abnormal lipid homeostasis

Availability

Mouse Genotype

Inppl1^tm1Glas/Inppl1^tm1Glas

Phox2a/Inppl1^tm1Ssch/Phox2a/Inppl1^tm1Ssch

Phox2a/Inppl1^tm1Ssch/Inppl1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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