Symbol
Name
ID

Trp63
transformation related protein 63
MGI:1330810

Phenotype annotations related to growth/size/body

Darker colors indicate more annotations

Human Phenotypes	Cystocele	Abnormality of the abdominal wall	Abdominal wall defect	Cloacal exstrophy	Inguinal hernia	Omphalocele	Bladder exstrophy	Short stature
Disease(s) Associated with TP63	Cystocele	Abnormality of the abdominal wall	Abdominal wall defect	Cloacal exstrophy	Inguinal hernia	Omphalocele	Bladder exstrophy	Short stature
bladder exstrophy-epispadias-cloacal exstrophy complex
Rapp-Hodgkin syndrome

Mouse Phenotypes

abnormal tooth development

absent tooth placode

absent teeth

supernumerary teeth

abnormal tooth root morphology

abnormal secondary palate development

abnormal palatal shelf fusion at midline

abnormal facial morphology

cleft palate

abnormal tongue epithelium morphology

absent tongue squamous epithelium

abnormal olfactory epithelium morphology

abnormal horizontal basal cell of olfactory epithelium morphology

gastric cyst

weight loss

abnormal abdominal wall morphology

urinary bladder exstrophy

abnormal ventral body wall morphology

kidney cyst

decreased fetal size

distended abdomen

Availability

Mouse Genotype

Trp63^tm1.1Elrf/Trp63^tm1.1Elrf

Trp63^tm1Brd/Trp63^tm1Brd

Trp63^tm1Fmc/Trp63^tm1Fmc

Trp63^tm1Sin/Trp63^tm1Sin

Trp63^tm2Brd/Trp63^tm2Brd

Trp63^tm1Cmis/Trp63⁺

Trp63^tm2.1Aam/Trp63^tm3.1Aam

Trp63^tm2.1Aam/Trp63^tm3.2Aam

Trp63^tm2.1Aam/Trp63^tm3Aam

Trp63^tm2Brd/Trp63⁺

Trp63^tm3.1Aam/Trp63⁺

Trp63^tm3Aam/Trp63⁺

Tg(KRT5-cre/PGR)1Der/0
Trp63^tm2Brd/Trp63^tm3.1Brd (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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