Symbol
Name
ID

Smarcb1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
MGI:1328366

Phenotype annotations related to neoplasm

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Lisch nodules

Retinal hamartoma

Lumbosacral hemangioma

Vestibular schwannoma

Bilateral vestibular schwannoma

Unilateral vestibular schwannoma

Neoplasm of the anterior pituitary

Uterine leiomyoma

Neoplasm of the skin

Neurofibroma

Peripheral schwannoma

Lipoma

Astrocytoma

Glioma

Ependymoma

Neuroma

Schwannoma

Choroid plexus carcinoma

Meningioma

Intracranial meningioma

Optic nerve sheath meningioma

Spinal meningioma

Spinal cord tumor

Malignant neoplasm of the central nervous system

Medulloblastoma

Neoplasm

Disease(s) Associated with SMARCB1

atypical teratoid rhabdoid tumor

schwannomatosis

schwannomatosis 1

vestibular schwannomatosis

Mouse Phenotypes		neoplasm	increased facial tumor incidence	increased T cell derived lymphoma incidence	increased rhabdomyoma incidence	increased lymphoma incidence	increased malignant tumor incidence	increased blastoma incidence	increased sarcoma incidence	increased brain tumor incidence	increased tumor incidence
Availability	Mouse Genotype	neoplasm	increased facial tumor incidence	increased T cell derived lymphoma incidence	increased rhabdomyoma incidence	increased lymphoma incidence	increased malignant tumor incidence	increased blastoma incidence	increased sarcoma incidence	increased brain tumor incidence	increased tumor incidence
	Smarcb1^em1Koke/Smarcb1^em1Koke	*
	Smarcb1^{Gt(OST32815)Lex}/Smarcb1⁺
	Smarcb1^tm1Gvk/Smarcb1⁺
	Smarcb1^tm1Mya/Smarcb1⁺
	Smarcb1^tm1Sho/Smarcb1⁺
	Smarcb1^tm2Sho/Smarcb1^tm2Sho Tg(GFAP-cre)#Gtm/0 (conditional)	*
	Smarcb1^tm1Sho/Smarcb1^tm3Sho Tg(Mx1-cre)1Cgn/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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