About   Help   FAQ
Symbol
Name
ID
Men1
multiple endocrine neoplasia 1
MGI:1316736
Phenotype annotations related to neoplasm
Darker colors indicate more annotations
Human Phenotypes
Subcutaneous lipoma
Multiple lipomas
Adenoma sebaceum
Thymoma
Pancreatic islet cell adenoma
Insulinoma
Zollinger-Ellison syndrome
Adrenocortical adenoma
Adrenocortical carcinoma
Pituitary adenoma
Pituitary corticotropic cell adenoma
Pituitary growth hormone cell adenoma
Pituitary null cell adenoma
Pituitary prolactin cell adenoma
Prolactinoma
Parathyroid adenoma
Thyroid adenoma
Neuroendocrine neoplasm
Carcinoid tumor
Glucagonoma
Angiofibromas
Disease(s) Associated with MEN1
multiple endocrine neoplasia type 1

Mouse Phenotypes
increased gastrointestinal tumor incidence
increased intestinal adenoma incidence
increased stomach tumor incidence
increased mammary gland tumor incidence
increased gland tumor incidence
increased adrenal gland tumor incidence
increased adrenal cortical tumor incidence
increased adrenocortical adenoma incidence
increased adrenal gland adenoma incidence
increased pheochromocytoma incidence
increased ovary tumor incidence
increased pancreas tumor incidence
increased pancreas adenoma incidence
increased pancreatic islet cell adenoma incidence
increased glucagonoma incidence
increased insulinoma incidence
increased pancreatic islet cell carcinoma incidence
increased parathyroid gland tumor incidence
increased parathyroid adenoma incidence
increased pituitary gland tumor incidence
increased pituitary adenohypophysis tumor incidence
increased prolactinoma incidence
increased pituitary adenoma incidence
increased testis tumor incidence
increased Leydig cell tumor incidence
increased thyroid tumor incidence
increased thyroid adenoma incidence
increased thyroid carcinoma incidence
increased carcinoma incidence
increased lung adenocarcinoma incidence
increased gonad tumor incidence
increased lung tumor incidence
increased tumor incidence
Availability Mouse Genotype
Men1tm1.1Ctre/Men1+
Men1tm1.1Gfk/Men1+
Men1tm1Ctre/Men1+
Men1tm1Rvt/Men1+
Men1tm1Zqw/Men1+
Men1tm2.1Gfk/Men1+
Men1tm1.2Ctre/Men1tm1.2Ctre
Tg(Ins2-cre)1Heed/0  (conditional)
Men1tm1.2Ctre/Men1tm1.2Ctre
Tg(Ins2-cre)1Dh/0  (conditional)
Men1tm1.2Ctre/Men1tm1.2Ctre
Tg(Ins2-cre)25Mgn/0  (conditional)
Men1tm1.2Zqw/Men1tm1.2Zqw
Tg(Ins2-cre)23Herr/0  (conditional)
Men1tm1Ctre/Men1tm1Ctre
Tg(Pdx1-cre)89.1Dam/0  (conditional)
Men1tm1Gfk/Men1tm1Gfk
Tg(Ins2-cre)25Mgn/0  (conditional)
Men1tm2.1Mmey/Men1tm2.1Mmey
Tg(Ins2-cre)23Herr/0  (conditional)
Men1tm1.2Ctre/Men1+
Tg(Ins2-cre)1Heed/0  (conditional)
Men1tm1.2Ctre/Men1+
Tg(Ins2-cre)1Dh/0  (conditional)
Men1tm1.2Ctre/Men1+
Tg(Ins2-cre)25Mgn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory