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Symbol
Name
ID
Men1
multiple endocrine neoplasia 1
MGI:1316736
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Elevated circulating parathyroid hormone level
Hypoglycemia
Fasting hyperinsulinemia
Hyperinsulinemic hypoglycemia
Hypercalcemia
Increased urinary cortisol level
Increased glucagon level
Increased circulating cortisol level
Disease(s) Associated with MEN1
multiple endocrine neoplasia type 1

Mouse Phenotypes
homeostasis/metabolism phenotype
abnormal blood homeostasis
decreased circulating glucose level
hypoglycemia
increased circulating corticosterone level
increased circulating insulin level
increased circulating calcium level
decreased circulating phosphate level
Availability Mouse Genotype
Men1tm1Ctre/Men1+
Men1tm1Mmey/Men1+
Men1tm1Rvt/Men1+ *
Men1tm1.2Ctre/Men1tm1.2Ctre
Tg(PTH-cre)4167Slib/0  (conditional)
Men1tm1.2Ctre/Men1tm1.2Ctre
Tg(Ins2-cre)1Heed/0  (conditional)
Men1tm1.2Ctre/Men1tm1.2Ctre
Tg(Ins2-cre)1Dh/0  (conditional)
Men1tm1.2Ctre/Men1tm1.2Ctre
Tg(Ins2-cre)25Mgn/0  (conditional)
Men1tm1.2Zqw/Men1tm1.2Zqw
Tg(Ins2-cre)23Herr/0  (conditional)
Men1tm1Ctre/Men1tm1Ctre
Tg(Pdx1-cre)89.1Dam/0  (conditional)
Men1tm1Ctre/Men1+
Tg(Pdx1-cre)89.1Dam/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/12/2019
MGI 6.13
The Jackson Laboratory