Symbol
Name
ID

Adgrv1
adhesion G protein-coupled receptor V1
MGI:1274784

Phenotype annotations related to hearing/vestibular/ear

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Congenital sensorineural hearing impairment
Disease(s) Associated with ADGRV1	Congenital sensorineural hearing impairment
Usher syndrome type 2C

Mouse Phenotypes

hearing/vestibular/ear phenotype

abnormal cochlear hair cell stereociliary bundle morphology

abnormal cochlear hair cell inter-stereocilial links morphology

absent cochlear hair bundle ankle links

abnormal inner hair cell stereociliary bundle morphology

abnormal orientation of outer hair cell stereociliary bundles

abnormal outer hair cell stereociliary bundle morphology

decreased outer hair cell stereocilia number

cochlear inner hair cell degeneration

cochlear outer hair cell degeneration

cochlear hair cell degeneration

pillar cell degeneration

organ of Corti degeneration

abnormal cochlear outer hair cell physiology

abnormal hair cell mechanoelectric transduction

abnormal auditory brainstem response

increased or absent threshold for auditory brainstem response

absent distortion product otoacoustic emissions

increased susceptibility to age-related hearing loss

deafness

Availability

Mouse Genotype

Adgrv1^frings/Adgrv1^frings

Adgrv1^m1/Adgrv1^m1

Adgrv1^mpc188H/Adgrv1^mpc188H

Adgrv1^rueda/Adgrv1^rueda

Adgrv1^{tm1.1(KOMP)Vlcg}/Adgrv1^{tm1.1(KOMP)Vlcg}

Adgrv1^tm1Msat/Adgrv1^tm1Msat

Adgrv1^tm1Pwh/Adgrv1^tm1Pwh

Adgrv1^tm2Msat/Adgrv1^tm2Msat

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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