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potassium inwardly-rectifying channel, subfamily J, member 10
Phenotype annotations related to hearing/vestibular/ear
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Sensorineural hearing impairment
Congenital sensorineural hearing impairment
Vestibular dysfunction
Hypoplasia of the cochlea
Cochlear malformation
Enlarged vestibular aqueduct
Disease(s) Associated with KCNJ10
EAST syndrome
Pendred Syndrome

Mouse Phenotypes
hearing/vestibular/ear phenotype
abnormal cochlea morphology
abnormal Reissner membrane morphology
collapsed Reissner membrane
distended Reissner membrane
cochlear inner hair cell degeneration
cochlear outer hair cell degeneration
abnormal scala media morphology
organ of Corti degeneration
abnormal stria vascularis morphology
abnormal tectorial membrane morphology
vestibular hair cell degeneration
abnormal crista ampullaris neuroepithelium morphology
utricular macular degeneration
vestibular saccular macula degeneration
abnormal cochlear endolymph ionic homeostasis
absent endocochlear potential
increased or absent threshold for auditory brainstem response
impaired hearing
Availability Mouse Genotype
Kcnj10tm1Lst/Kcnj10tm1Lst *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory