|
Symbol Name ID |
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10 MGI:1194504 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Incomplete partition of the cochlea type II |
Enlarged vestibular aqueduct |
Sensorineural hearing impairment |
| Disease(s) Associated with KCNJ10 | |||
| autosomal recessive nonsyndromic deafness 4 | |||
| EAST syndrome |
| Mouse Phenotypes | hearing/vestibular/ear phenotype |
abnormal cochlea morphology |
abnormal Reissner membrane morphology |
collapsed Reissner membrane |
distended Reissner membrane |
cochlear inner hair cell degeneration |
cochlear outer hair cell degeneration |
abnormal scala media morphology |
organ of Corti degeneration |
abnormal stria vascularis morphology |
abnormal tectorial membrane morphology |
vestibular hair cell degeneration |
abnormal crista ampullaris neuroepithelium morphology |
utricular macular degeneration |
vestibular saccular macula degeneration |
abnormal cochlear endolymph ionic homeostasis |
absent endocochlear potential |
increased or absent threshold for auditory brainstem response |
impaired hearing |
|
| Availability | Mouse Genotype | |||||||||||||||||||
| Kcnj10tm1Lst/Kcnj10tm1Lst | * | |||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/16/2024 MGI 6.23 |
|
|
|
||
Analysis Tools