Symbol
Name
ID

Nr2e1
nuclear receptor subfamily 2, group E, member 1
MGI:1100526

Phenotype annotations related to vision/eye

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

vision/eye phenotype

abnormal retina vasculature morphology

abnormal retina ganglion cell morphology

absent photoreceptor outer segment

abnormal optic nerve morphology

optic nerve degeneration

abnormal optic stalk morphology

persistence of hyaloid vascular system

abnormal retina morphology

abnormal retina ganglion layer morphology

disorganized retina ganglion layer

abnormal retina inner nuclear layer morphology

thin retina inner nuclear layer

disorganized retina inner nuclear layer

abnormal retina inner plexiform layer morphology

abnormal retina nerve fiber layer morphology

abnormal retina outer nuclear layer morphology

thin retina outer nuclear layer

disorganized retina outer nuclear layer

abnormal retina outer plexiform layer morphology

abnormal retina photoreceptor layer morphology

increased susceptibility to age-related retinal degeneration

abnormal eye electrophysiology

blindness

Availability

Mouse Genotype

Nr2e1^frc/Nr2e1^frc

Nr2e1^tm1Rtyu/Nr2e1^tm1Rtyu

Nr2e1^tm1Rev/Nr2e1^tm1Rev
Tg(Nes-cre)1Kln/0 (conditional)

Nr2e1^tm2Gsc/Nr2e1^tm2Gsc
Tg(Camk2a-cre)2Gsc/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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